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DDIT3 抗体 (AA 87-192)

This anti-DDIT3 antibody is a 小鼠 单克隆 antibody detecting DDIT3 in IHC, ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN7539832
发货至: 中国

Quick Overview for DDIT3 抗体 (AA 87-192) (ABIN7539832)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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宿主

  • 127
  • 12
小鼠

克隆类型

  • 115
  • 24
单克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

4E8E9
  • 抗原表位

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    AA 87-192

    原理

    DDIT3 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DDIT3 (AA: 87-192) expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    DDIT3

    背景

    This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

    分子量

    19.2 kDa

    基因ID

    1649

    UniProt

    P35638

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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