DDIT3 抗体 (AA 87-192)
Quick Overview for DDIT3 抗体 (AA 87-192) (ABIN7539832)
抗原
See all DDIT3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 87-192
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原理
- DDIT3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human DDIT3 (AA: 87-192) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
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别名
- DDIT3
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背景
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
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分子量
- 19.2 kDa
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基因ID
- 1649
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UniProt
- P35638
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途径
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
抗原
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