NOTCH4 抗体 (AA 118-357)
Quick Overview for NOTCH4 抗体 (AA 118-357) (ABIN7539818)
抗原
See all NOTCH4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 118-357
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原理
- NOTCH4 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human NOTCH4 (AA: 118-357) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- NOTCH4 (Notch 4 (NOTCH4))
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别名
- NOTCH4
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背景
- This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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分子量
- 209.6 kDa
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基因ID
- 4855
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UniProt
- Q99466
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途径
- Notch Signaling
抗原
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