Mre11 抗体 (AA 182-582)
Quick Overview for Mre11 抗体 (AA 182-582) (ABIN7539803)
抗原
See all Mre11 (MRE11A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 182-582
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原理
- MRE11 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human MRE11 (AA: 182-582) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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别名
- MRE11
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背景
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This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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分子量
- 80.6 kDa
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基因ID
- 4361
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UniProt
- P49959
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途径
- DNA Damage Repair
抗原
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