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DCLK2 抗体 (AA 652-766)

This anti-DCLK2 antibody is a 小鼠 单克隆 antibody detecting DCLK2 in ELISA, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7539736
发货至: 中国

Quick Overview for DCLK2 抗体 (AA 652-766) (ABIN7539736)

抗原

See all DCLK2 抗体
DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

适用

  • 27
  • 13
  • 3

宿主

  • 26
  • 1
小鼠

克隆类型

  • 26
  • 1
单克隆

标记

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  • 1
  • 1
  • 1
  • 1
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This DCLK2 antibody is un-conjugated

应用范围

  • 20
  • 13
  • 6
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ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

3H1G4
  • 抗原表位

    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 652-766

    原理

    DCLK2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

    别名

    DCLK2

    背景

    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

    分子量

    83.6 kDa

    基因ID

    166614

    UniProt

    Q8N568
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