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DCLK2 抗体 (C-Term)

DCLK2 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499718
发货至: 中国
  • 抗原 See all DCLK2 抗体
    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
    抗原表位
    • 13
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 30
    • 1
    克隆类型
    • 30
    • 1
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCLK2 antibody is un-conjugated
    应用范围
    • 24
    • 18
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    DCLK2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DCLK2.
    亚型
    IgG
    Top Product
    Discover our top product DCLK2 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
    别名
    Doublecortin-Like Kinase 2 (DCLK2 产品)
    背景
    DCLK2 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK2 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK1 and DCLK2 transcripts are present in human fetal brain and the developing mouse embryo, suggesting that DCLK1 and DCLK2 may play roles in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization. Unlike DCLK1, DCLK2 expression does not change in DCX-null mice.Synonyms: CLICK2, DCAMKL2, DCDC3B, DCK2, DCLK2, DKFZp761I032, Serine/threonine-protein kinase DCLK2
    基因ID
    166614
    NCBI登录号
    NP_001035350
    UniProt
    Q8N568
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