Cyclin B3 抗体 (AA 142-363)
Quick Overview for Cyclin B3 抗体 (AA 142-363) (ABIN7539697)
抗原
See all Cyclin B3 (CCNB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 142-363
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原理
- CCNB3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CCNB3 (AA: 142-363) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Cyclin B3 (CCNB3)
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别名
- CCNB3
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背景
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 158 kDa
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基因ID
- 85417
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UniProt
- Q8WWL7
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途径
- Cell Division Cycle, Chromatin Binding
抗原
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