PKD1 抗体 (AA 3682-3873)
Quick Overview for PKD1 抗体 (AA 3682-3873) (ABIN7539645)
抗原
See all PKD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3682-3873
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原理
- PKD1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of mouse PKD1 (AA: 3682-3873) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
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别名
- PKD1
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背景
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Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate.
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分子量
- 466 kDa
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基因ID
- 18763
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UniProt
- O08852
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途径
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
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