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VEGFC 抗体 (Biotin)

This anti-VEGFC antibody is a 兔 多克隆 antibody detecting VEGFC in ELISA. Suitable for 大鼠.
产品编号 ABIN7539286
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VEGFC 抗体 (Biotin) (ABIN7539286)

抗原

See all VEGFC 抗体
VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This VEGFC antibody is conjugated to Biotin

应用范围

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ELISA
  • 原理

    VEGF-C antibody

    特异性

    Chromosomal location:16p11

    纯化方法

    Antigen-affinity purified

    免疫原

    Recombinant rat VEGF-C (RT #R20-015)
  • 应用备注

    ELISA: Use 1-10 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, BSA (50x), 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

    别名

    VEGF-C

    背景

    Vascular endothelial growth factor C, Vegfc,VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.

    基因ID

    114111

    NCBI登录号

    NM_053653, NP_446105

    UniProt

    O35757

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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