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FLT4 抗体 (Biotin)

This anti-FLT4 antibody is a 兔 多克隆 antibody detecting FLT4 in ELISA. Suitable for 人.
产品编号 ABIN7539262
发货至: 中国

Quick Overview for FLT4 抗体 (Biotin) (ABIN7539262)

抗原

See all FLT4 抗体
FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLT4 antibody is conjugated to Biotin

应用范围

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ELISA
  • 原理

    VEGFR-3/FLT-4 antibody

    特异性

    Chromosomal location:5q35.3

    纯化方法

    Antigen-affinity purified

    免疫原

    Recombinant human sFLT-4 (D1-7) (ABIN1589554 and ABIN1589553)
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, BSA (50x), 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

    别名

    VEGFR-3/FLT-4

    背景

    Vascular endothelial growth factor receptor-3, FLT4, PCL, LMPH1A, VEGFR3, fms-related tyrosine kinase 4,Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1-D7), a single transmembrane (TM) helix and cytoplasmic region with a tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelia cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system.

    基因ID

    2324

    NCBI登录号

    NM_002020, NP_002011

    UniProt

    P35916

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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