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Amphiregulin 抗体

This anti-Amphiregulin antibody is a 兔 多克隆 antibody detecting Amphiregulin in WB 和 IF. Suitable for 人.
产品编号 ABIN7539230
发货至: 中国

Quick Overview for Amphiregulin 抗体 (ABIN7539230)

抗原

See all Amphiregulin (AREG) 抗体
Amphiregulin (AREG)

适用

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宿主

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克隆类型

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多克隆

标记

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This Amphiregulin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    Amphiregulin antibody

    纯化方法

    Protein A purified

    免疫原

    recombinant human Amphiregulin
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    Amphiregulin (AREG)

    别名

    Amphiregulin

    背景

    AREG, AR, SDGF, AREGB, CRDGF,Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.

    基因ID

    374

    NCBI登录号

    NM_001657, NP_001648

    UniProt

    P15514

    途径

    RTK signaling, EGFR Signaling Pathway
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