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CD4 抗体 (AA 412-458)

This anti-CD4 antibody is a 兔多克隆 antibody detecting CD4 in WB 和 ELISA. Suitable for 人.

Western blot demonstrating our polyclonal detecting recombinant human CD4 (P01730) at 1in2000 dilution (1 = Marker, 2 =CD4 (1 ng), 3 =CD4 (5 ng), 4=CD4 (10 ng),4=CD4 (50 ng) ) (CD4 抗体 (AA 412-458))

ELISA Plates were coated with 1 μg/mL recombinant human CD4 protein, our polyclonal anti-CD4 was added at different concentrations and detected with an anti-rabbit HRP. (CD4 抗体 (AA 412-458))

2 images

产品编号 ABIN7538099

发货至: 中国

Quick Overview for CD4 抗体 (AA 412-458) (ABIN7538099)

抗原

See all CD4 抗体

CD4

适用

422
231
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人

宿主

427
165
126
7
3
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1
1

兔

克隆类型

多克隆

标记

This CD4 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

Discover our top product CD4 Primary Antibody

抗原表位
32

31

26

16

16

16

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10

10

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5

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1

1
AA 412-458

原理

Rabbit polyclonal antibodies to CD4

特异性

CD4 full length protein

交叉反应（详细）

May cross-react with other species

纯化方法

Immunogen affinity column

免疫原

IGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI - alphaalpha 412-458

亚型

IgG, IgM
anti-CD4 (CD4) (AA 385-457) antibody
CD4 适用: 人, 小鼠, 大鼠, 小鸡, Pig FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 适用: 人, 小鼠, 大鼠, 小鸡, 猴, 犬, Pig, 兔, Cat, Cow, 绵羊, 豚鼠, 山羊, 马, Avian, 驴, Hamster WB, IHC 宿主: 山羊 Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 适用: 人 FACS, WB, MS 宿主: 小鼠 Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) (AA 301-400) antibody
CD4 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 适用: 小鼠 FACS, IP, IHC (fro), ICC, Func 宿主: 大鼠 Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-241 FITC

anti-CD4 (CD4) antibody (PE)
CD4 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-35 PE

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-241 PE

anti-CD4 (CD4) (AA 26-200) antibody
CD4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot: 0.1-1.0 μg/mL

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Glycine pH 7.2

储存条件

4 °C,-80 °C

储存方法

Short term up to 1 month at 2-8°C, long term can be held for up to five years at -70°C
抗原

CD4

别名

CD4

背景

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages

分子量

51111 Da

基因ID

920

NCBI登录号

NP_000607

UniProt

P01730

途径

TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

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