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Interleukin 17a 抗体

This anti-Interleukin 17a antibody is a 小鼠 单克隆 antibody detecting Interleukin 17a in ICFC. Suitable for 小鼠.
产品编号 ABIN7536930
发货至: 中国

Quick Overview for Interleukin 17a 抗体 (ABIN7536930)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

  • 85
  • 45
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小鼠

宿主

  • 66
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  • 16
  • 5
  • 2
  • 2
小鼠

克隆类型

  • 71
  • 56
  • 1
单克隆

标记

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  • 1
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This Interleukin 17a antibody is un-conjugated

应用范围

  • 75
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Intracellular Flow Cytometry (ICFC)

克隆位点

17F3
  • 原理

    Purified Anti-Mouse IL-17A Antibody [17F3]

    纯化方法

    Purified

    亚型

    IgG1, kappa
  • 应用备注

    Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

    说明

    Matching Isotype Control: (ABIN7469768)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months. Do not freeze.

    有效期

    12 months
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A

    背景

    IL-17A,Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.

    基因ID

    16171

    UniProt

    Q62386
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