IL7R 抗体
Quick Overview for IL7R 抗体 (ABIN7536899)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Mouse CD127/IL-7RA Antibody [A7R34]
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纯化方法
- Purified
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亚型
- IgG2a, kappa
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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说明
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Matching Isotype Control: (ABIN7469837)
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Do not freeze.
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有效期
- 12 months
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- CD127/IL-7RA
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背景
- CD127,Interleukin-7 receptor subunit alpha,Il7r,IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA,CD127,CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
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基因ID
- 16197
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UniProt
- P16872
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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