SIGLEC8 抗体 (Extracellular Domain) (PE)
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Quick Overview for SIGLEC8 抗体 (Extracellular Domain) (PE) (ABIN7506011)
抗原
See all SIGLEC8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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原理
- Anti-Hu SIGLEC8 PE
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特异性
- The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
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亚型
- IgG1
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anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibody
SIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibodySIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibodySIGLEC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibodySIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D3 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-363) antibodySIGLEC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibodyVerified SIGLEC8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) antibodySIGLEC8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibodySIGLEC8 适用: 人 ELISA, IP, FACS 宿主: 小鼠 Monoclonal 7C9 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibodySIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) antibodySIGLEC8 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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别名
- SIGLEC8
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背景
- Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2
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基因ID
- 27181
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UniProt
- Q9NYZ4
抗原
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