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BTLA 抗体

This 小鼠 单克隆 anti-BTLA antibody (Clone MIH26) specifically detects BTLA in FACS. The antibody is reactive with 人 和 Non-Human Primate samples.
产品编号 ABIN7505891
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for BTLA 抗体 (ABIN7505891)

抗原

See all BTLA 抗体
BTLA (B and T Lymphocyte Associated (BTLA))

适用

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人, Non-Human Primate

宿主

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小鼠

克隆类型

  • 74
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  • 2
单克隆

标记

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This BTLA antibody is un-conjugated

应用范围

  • 56
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Flow Cytometry (FACS)

克隆位点

MIH26
  • 原理

    Anti-Hu CD272 Purified

    特异性

    The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.

    纯化方法

    Purified by protein-A affinity chromatography.

    免疫原

    cells transfected with human CD272

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 2-5 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    BTLA (B and T Lymphocyte Associated (BTLA))

    别名

    CD272

    背景

    B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1

    基因ID

    151888

    UniProt

    Q7Z6A9

    途径

    Cancer Immune Checkpoints
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