BTLA 抗体
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北京 101111
Quick Overview for BTLA 抗体 (ABIN7505891)
抗原
See all BTLA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD272 Purified
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特异性
- The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
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纯化方法
- Purified by protein-A affinity chromatography.
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免疫原
- cells transfected with human CD272
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亚型
- IgG2a kappa
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应用备注
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- BTLA (B and T Lymphocyte Associated (BTLA))
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别名
- CD272
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背景
- B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
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基因ID
- 151888
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UniProt
- Q7Z6A9
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途径
- Cancer Immune Checkpoints
抗原
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