Cyclin D1 抗体 (APC)
Quick Overview for Cyclin D1 抗体 (APC) (ABIN7489415)
抗原
See all Cyclin D1 (CCND1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Cyclin D1 APC Antibody
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产品特性
- The clone C-D1A5, a mouse monoclonal antibody selectively binds to ~34 kD protein is encoded by the CCND1 gene known as Cyclin D1. It is expressed in all adult human tissues except for cells derived from bone marrow stem cell lines (both lymphoid and myeloid), Cyclin D1 is an important regulator of cell cycle progression and can function as a transcriptional co-regulator. The overexpression of cyclin D1 has been linked to the development and progression of cancer cells.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human full length recombinant cyclin D1 protein
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- Cyclin D1 (CCND1)
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别名
- Cyclin D1
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基因ID
- 5788
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NCBI登录号
- NM_002838
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UniProt
- P08575
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途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
抗原
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