ICAM1 抗体 (mFluor™510)
Quick Overview for ICAM1 抗体 (mFluor™510) (ABIN7489331)
抗原
See all ICAM1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD54 mFluor™ 500 Antibody
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产品特性
- The clone LB-2 specifically binds with CD54 also known as Intercellular adhesion molecule-1 (ICAM-1), a cell surface antigen expressed by various types of human immune and non-immune cells. CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the Ig supergene family and is a surrogate marker of antigen presenting cell activation. CD54 is expressed mostly on endothelial cells. It also weakly expressed by naive B and T cells and moderately expressed on activated B and T cells as well as monocytes. CD54 is highly expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, and B-lymphoblastoid cells. The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- MHC Class II antigen negative human Blymphoblastoid cell line
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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别名
- CD54
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基因ID
- 3383
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NCBI登录号
- NP_000192
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UniProt
- P05362
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
抗原
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