Recombinant Hemagglutinin 抗体
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Quick Overview for Recombinant Hemagglutinin 抗体 (ABIN7487730)
抗原
See all Hemagglutinin (HA) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-HA [CR6261], Human IgG1, kappa
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特异性
- This antibody binds hemaglutinin of most group 1 influenza viruses. CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1/HA2.
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产品特性
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Original Species of Ab: Human
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was isolated using phage display from the IgM+ memory B cells of a healthy individual vaccinated against influenza.
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亚型
- IgG1 kappa
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anti-Hemagglutinin antibody (Influenza A Virus) (AA 128-143)
HA 适用: Influenza A Virus WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H9N2) (AA 9-28)HA 适用: Influenza A Virus H9N2 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H1N1 (A/California/04/2009)) (AA 151-250)HA 适用: Influenza A Virus H1N1, Virus ELISA, WB, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza Virus)HA 适用: Influenza Virus ELISA, WB, IP, DB 宿主: 小鼠 Monoclonal HA-C5 unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H3N2 (A/Shangdong/9/93))HA 适用: Influenza A Virus H3N2 ELISA, WB 宿主: 小鼠 Monoclonal B264M unconjugated
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应用备注
- The antibody neutralizes the virus by blocking conformational rearrangements associated with membrane fusion. CR6261 neutralizes multiple influenza subtypes, including H1, H2, H5, H6, H8, and H9, and protects mice from lethal challenge with H1N1 and H5N1 viruses when administered up to five days post-infection (PMID: 19251591). It is reported that Oseltamivir/Zanamivir may congruously improve the therapeutic efficacy of CR6261 (PMID: 22693576).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Hemagglutinin (HA)
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别名
- Hemagglutinin
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物质类
- Influenza Protein
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背景
- Hemagglutinin, Avian Influenza Virus, AIV, H1N1, H5N1, Influenza A virus
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UniProt
- Q9WFX3
抗原
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