Recombinant CRP 抗体
Quick Overview for Recombinant CRP 抗体 (ABIN7487718)
抗原
See all CRP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CRP [P03], Rabbit IgG, kappa
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特异性
- This antibody reacts with human C reactive protein, which is a pentameric protein found in blood plasma. It is an acute phase reactive protein of hepatic origin. It is an important defense molecule for the body and its plasma concentration increases sharply during tissue damage, inflammation and bacterial infection. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing BALB/c mice with C-reactive protein extracted from human plasma.
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亚型
- IgG kappa
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应用备注
- Indirect ELISA was used for the primary screening of the hybridomas showing selective binding for human CRP. Spicy Root peroxidase labeled scFv P03 was used for the identification of natural CRP extracted from denatured and non-denatured blood in a western blot assay. This antibody in combination with P24 was also used in the double antibody sandwich detection of natural human CRP. The combination of P03 and P24 antibody was also used for the generation of time-resolved fluorescence immunoassay card for detection of C-reactive protein (CN105842440).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CRP (C-Reactive Protein (CRP))
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别名
- CRP
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背景
- C reactive protein, PTX1, C-reactive protein
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UniProt
- P02741
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途径
- Carbohydrate Homeostasis
抗原
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