The antibody to CD5 is used for the classification of lymphoid neoplasm. CD5 is exprimed by the majority of T-cell lymphoma and is also found on B-cells in some cases of chronic lymphatic leukaemia and centrocytic lymphoma. Normally it is not found in other forms of lymphoid neoplasm e.g. follicular lymphoma, Hairy Cell Lymphoma and Large Cell Lymphoma. CD5 is a lymphocyte surface molecule with a molecular weight of 67 kDa. It is exprimed by 95 % of thymocytes and app. 72 % of peripheral blood lymphocytes. In lymph nodes the antigen is detected in the T-cell region mainly. CD5 is over-expressed in leukaemia and T-cell lymphoma and may also be detected in a subpopulation of activated B-cells. Human CD5 Molecule.
纯化方法
Antibody solution
免疫原
Synthetic Protein, corresponding to a sequence of human CD5 molecule
Paraffin sections are pre-treated with 1 mM EDTA ( pH 8.0) in an autoclave (2 min under full pressure, cooling 15-20 min.),Tonsil,IHC(C, P), FACS,60 min at RT,(liquid conc.) 1:10-1:25
限制
仅限研究用
缓冲液
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μl working solution / test).
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.