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Recombinant MSH6 抗体 (AA 1-100)

This anti-MSH6 antibody is a 兔 单克隆 antibody detecting MSH6 in IHC. Suitable for 人.
产品编号 ABIN7477533
发货至: 中国

Quick Overview for Recombinant MSH6 抗体 (AA 1-100) (ABIN7477533)

抗原

See all MSH6 抗体
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

抗体类型

Recombinant Antibody

适用

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宿主

  • 90
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克隆类型

  • 92
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  • 1
单克隆

标记

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This MSH6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

906R
  • 抗原表位

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    AA 1-100

    原理

    MSH6 antibody (906R)

    免疫原

    Recombinant fragment (around aa 1-100) of human MSH6 protein (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    IHC 1:75-1:150

    说明

    Positive Control: Tonsil: Virtually all mantle zone B-cells must show an at least weak to moderate nuclear staining. A moderate to strong nuclear staining must be seen in the germinal centre B-cells.

    Product Description/Background: MSH6 antibody validated for immunohistochemistry on 76 different Normal Tissues

    Negative Control: Colon adenocarcinoma with previously documented loss of MSH6 expression: Nuclear staining should be absent in cancer cells, while a nuclear staining must be seen in stromal and inflammatory cells.

    实验流程

    Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:100 at 37 °C for 60 minutes.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

    有效期

    24 months
  • 抗原

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    别名

    MSH6

    背景

    Gene Alias: DNA mismatch repair protein Msh6, G/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, MSH6, mutS (E. coli) homolog 6, MutS alpha 160 kDa subunit, MutS-alpha 160 kDa subunit, p160, Sperm associated protein

    UniProt

    P52701

    途径

    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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