VRK1 抗体
Quick Overview for VRK1 抗体 (ABIN7469655)
抗原
See all VRK1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human VRK1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Vaccinia Related Kinase 1 (VRK1) (AA 287-396) antibody
VRK1 适用: 人 WB, ELISA, IP, IF, RNAi 宿主: 小鼠 Monoclonal 4F9 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (N-Term) antibodyVRK1 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 5D1 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 257-396) antibodyVRK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 1-396) antibodyVRK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 1-396) antibodyVRK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人 WB 宿主: 小鼠 Monoclonal 5C1 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 287-396) antibodyVRK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (Internal Region) antibodyVRK1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- VRK1 (Vaccinia Related Kinase 1 (VRK1))
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别名
- VRK1
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背景
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Synonyms: VRK serine/threonine kinase 1 , PCH1 , PCH1A
Background: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq]
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分子量
- 45 kDa
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基因ID
- 7443
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UniProt
- Q99986
抗原
-
