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SETD2 抗体 (N-Term)

This 兔 多克隆 anti-SETD2 antibody specifically detects SETD2 in WB, IF, IHC (p) 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7469603
发货至: 中国
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Quick Overview for SETD2 抗体 (N-Term) (ABIN7469603)

抗原

See all SETD2 抗体
SETD2 (SET Domain Containing 2 (SETD2))

适用

  • 27
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宿主

  • 23
  • 4

克隆类型

  • 23
  • 4
多克隆

标记

  • 15
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  • 1
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This SETD2 antibody is un-conjugated

应用范围

  • 12
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

质量等级

KO Validated
  • 抗原表位

    • 9
    • 2
    • 1
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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human HYPB/SETD2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    SETD2 (SET Domain Containing 2 (SETD2))

    别名

    HYPB/SETD2

    背景

    Synonyms: SET domain containing 2, histone lysine methyltransferase , HBP231 , HIF-1 , HIP-1 , HSPC069 , HYPB , KMT3A , LLS , SET2 , p231HBP

    Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq]

    分子量

    288 kDa

    基因ID

    29072

    UniProt

    Q9BYW2

    途径

    Tube Formation
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