ERCC1 抗体 (Center)
Quick Overview for ERCC1 抗体 (Center) (ABIN7469352)
抗原
See all ERCC1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Center
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ERCC1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 151-250) antibody
ERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-297) antibodyERCC1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5A2D1 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 191-281) antibodyERCC1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ERCC1-2318 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 151-297) antibodyERCC1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1E5B3 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-120) antibodyERCC1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F9E9 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-323) antibodyERCC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 207-281) antibodyERCC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (Internal Region) antibodyERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (Internal Region) antibodyERCC1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-323) antibodyERCC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2 , PC-12 , Rat2 Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
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别名
- ERCC1
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背景
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Synonyms: ERCC excision repair 1, endonuclease non-catalytic subunit , COFS4 , RAD10 , UV20
Background: The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq]
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分子量
- 33 kDa
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基因ID
- 2067
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UniProt
- P07992
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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