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WISP2 抗体

This anti-WISP2 antibody is a 兔 多克隆 antibody detecting WISP2 in WB. Suitable for 人.
产品编号 ABIN7469275
发货至: 中国

Quick Overview for WISP2 抗体 (ABIN7469275)

抗原

See all WISP2 抗体
WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

适用

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宿主

  • 42
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克隆类型

  • 43
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多克隆

标记

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This WISP2 antibody is un-conjugated

应用范围

  • 38
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Western Blotting (WB)
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human WISP2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

    别名

    WISP2

    背景

    Synonyms: cellular communication network factor 5 , CT58 , CTGF-L , WISP2

    Background: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq]

    分子量

    27 kDa

    基因ID

    8839

    UniProt

    O76076

    途径

    WNT signaling, Growth Factor Binding
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