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VAV1 抗体 (pTyr174)

This anti-VAV1 antibody is a 兔多克隆 antibody detecting VAV1 in WB. Suitable for 人.

产品编号 ABIN7469173

发货至: 中国

Quick Overview for VAV1 抗体 (pTyr174) (ABIN7469173)

抗原

See all VAV1 抗体

VAV1 (Vav 1 Oncogene (VAV1))

适用

66
38
24
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

50
3
2
2
2
2
2
2
1
1
1
1

This VAV1 antibody is un-conjugated

应用范围

49
35
18
9
8
8
7
2
1
1
1
1

Western Blotting (WB)

Discover our top product VAV1 Primary Antibody

抗原表位
14

14

7

5

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr174

交叉反应

人

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Carrier-protein conjugated synthetic peptide surrounding phospho Tyr174 of human VAV1. The exact sequence is proprietary.

亚型

IgG
anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody
VAV1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2E11 unconjugated

anti-Vav 1 Oncogene (VAV1) (AA 565-795) antibody
VAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (pTyr174) antibody
VAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibody
VAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9C1 unconjugated

anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibody
VAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated

anti-Vav 1 Oncogene (VAV1) (N-Term) antibody
VAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (Center) antibody
VAV1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (Tyr174) antibody
VAV1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (Tyr174) antibody
VAV1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vav 1 Oncogene (VAV1) (AA 100-200) antibody
VAV1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: Jurkat (serum starvation for 15 min then 0.13 μg/mL anti-T-cell receptor antibody (clone 305) treatment for 5 min) Validation: Orthogonal

限制

仅限研究用
状态

Liquid

浓度

0.23 mg/mL

缓冲液

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

VAV1 (Vav 1 Oncogene (VAV1))

别名

vav guanine nucleotide exchange factor 1

背景

Synonyms: vav guanine nucleotide exchange factor 1 , VAV
Background: The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]

分子量

98 kDa

基因ID

7409

UniProt

P15498

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling

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