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ULK1 抗体 (pSer758)

This anti-ULK1 antibody is a 兔 多克隆 antibody detecting ULK1 in WB. Suitable for 人.
产品编号 ABIN7469130
发货至: 中国

Quick Overview for ULK1 抗体 (pSer758) (ABIN7469130)

抗原

See all ULK1 抗体
ULK1 (Unc-51 Like Kinase 1 (ULK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ULK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer758

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide surrounding phospho Ser758 of human ULK1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MCF-7 ( starvation for 16 hr incubated in EBSS for 4 hr and 200 nM Rapamycin treatment for 0.5 hr) Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.3 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ULK1 (Unc-51 Like Kinase 1 (ULK1))

    别名

    unc-51 like autophagy activating kinase 1

    背景

    Synonyms: unc-51 like autophagy activating kinase 1 , ATG1 , ATG1A , UNC51 , Unc51.1 , hATG1

    Background: Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells.

    分子量

    113 kDa

    基因ID

    8408

    UniProt

    O75385

    途径

    Regulation of Cell Size, Autophagy
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