TNFSF9 抗体
Quick Overview for TNFSF9 抗体 (ABIN7469101)
抗原
See all TNFSF9 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human 4-1BBL / CD137L. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 101-200) antibody
TNFSF9 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 42-253) antibodyTNFSF9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 105-309) antibodyTNFSF9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) antibodyTNFSF9 适用: 人 FACS, IHC, StM 宿主: 小鼠 Monoclonal CD137L-1547 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 52-254) antibodyTNFSF9 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM68 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Extracellular Domain) antibodyTNFSF9 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 41B436 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 52-254) antibodyTNFSF9 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 145-254) antibodyTNFSF9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (AA 145-254) antibodyTNFSF9 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: HCT116
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
-
别名
- TNF superfamily member 9
-
背景
-
Synonyms: TNF superfamily member 9 , 4-1BB-L , CD137L , TNLG5A
Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
-
分子量
- 27 kDa
-
基因ID
- 8744
-
UniProt
- P41273
-
途径
- Activated T Cell Proliferation, Cancer Immune Checkpoints
抗原
-
