RPS6KB1 抗体
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北京 101111
Quick Overview for RPS6KB1 抗体 (ABIN7468893)
抗原
See all RPS6KB1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human p70 S6K. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 1-352) antibody
RPS6KB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 416-525) antibodyRPS6KB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) antibodyRPS6KB1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr229) antibodyRPS6KB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pSer424), (pThr421) antibodyRPS6KB1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 361-525) antibodyRPS6KB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 91-352) antibodyRPS6KB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 416-525) antibodyRPS6KB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 416-525) antibodyRPS6KB1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pSer371) antibodyRPS6KB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa , C8D30 , Raw264.7 , C2C12 , PC-12 Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7), 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
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别名
- ribosomal protein S6 kinase B1
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背景
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Synonyms: ribosomal protein S6 kinase B1 , PS6K , S6K , S6K-beta-1 , S6K1 , STK14A , p70 S6KA , p70(S6K)-alpha , p70-S6K , p70-alpha
Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq]
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分子量
- 59 kDa
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基因ID
- 6198
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UniProt
- P23443
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect
抗原
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