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RAD17 抗体 (pSer645)

This anti-RAD17 antibody is a 兔多克隆 antibody detecting RAD17 in WB. Suitable for 人.

产品编号 ABIN7468847

发货至: 中国

Quick Overview for RAD17 抗体 (pSer645) (ABIN7468847)

抗原

See all RAD17 抗体

RAD17

适用

99
30
19
5
4
4
3
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

51
6
5
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1

This RAD17 antibody is un-conjugated

应用范围

54
33
26
26
14
12
11
10
6
5
4
1
1
1
1

Western Blotting (WB)

Discover our top product RAD17 Primary Antibody

抗原表位
19

15

9

7

7

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer645

交叉反应

人

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Carrier-protein conjugated synthetic peptide surrounding phospho Ser645 of human Rad17. The exact sequence is proprietary.

亚型

IgG
anti-RAD17 (RAD17) (AA 1-584) antibody
RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) (AA 1-110) antibody
RAD17 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated

anti-RAD17 (RAD17) (AA 391-670) antibody
RAD17 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) (AA 1-270) antibody
RAD17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) (C-Term) antibody
RAD17 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) (C-Term) antibody
RAD17 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) (C-Term) antibody
RAD17 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) (AA 621-670) antibody
RAD17 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-RAD17 (RAD17) antibody
RAD17 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3-10E-010 unconjugated

anti-RAD17 (RAD17) (pSer646) antibody
RAD17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: HeLa Validation: Orthogonal

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

RAD17

别名

RAD17 checkpoint clamp loader component

背景

Synonyms: RAD17 checkpoint clamp loader component , CCYC , HRAD17 , R24L , RAD17SP , RAD24
Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq]

分子量

77 kDa

基因ID

5884

UniProt

O75943

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