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PKD2 抗体 (C-Term)

This anti-PKD2 antibody is a 兔 多克隆 antibody detecting PKD2 in WB, IHC (p) 和 IHC (wm). Suitable for 人.
产品编号 ABIN7468758
发货至: 中国

Quick Overview for PKD2 抗体 (C-Term) (ABIN7468758)

抗原

See all PKD2 抗体
PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))
  • 抗原表位

    • 15
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    C-Term

    交叉反应

    人, 斑马鱼

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Polycystin 2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

    别名

    polycystin 2, transient receptor potential cation channel

    背景

    Synonyms: polycystin 2, transient receptor potential cation channel , APKD2 , PC2 , PKD4 , Pc-2 , TRPP2

    Background: This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. [provided by RefSeq]

    分子量

    110 kDa

    基因ID

    5311

    UniProt

    Q13563

    途径

    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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