PMS2CL/PMS2 抗体 (N-Term)
PMS2
适用: 人
IP, WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all PMS2CL/PMS2 (PMS2) products
- PMS2CL/PMS2 (PMS2) (PMS1 Homolog 2, Mismatch Repair System Component (PMS2))
- 抗原表位
- N-Term
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
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标记
- This PMS2CL/PMS2 antibody is un-conjugated
- 应用范围
- Immunoprecipitation (IP), Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human PMS2. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: human PMS2-transfected 293T cells , A431 , HeLa , HepG2 Validation: Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PMS2CL/PMS2 (PMS2) (PMS1 Homolog 2, Mismatch Repair System Component (PMS2))
- 别名
- PMS1 homolog 2, mismatch repair system component (PMS2 产品)
- 别名
- HNPCC4 antibody, PMS2CL antibody, PMSL2 antibody, PMS1 homolog 2, mismatch repair system component antibody, PMS2 antibody
- 背景
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Synonyms: PMS1 homolog 2, mismatch repair system component , HNPCC4 , MLH4 , PMS2CL , PMSL2
Background: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]
- 分子量
- 96 kDa
- 基因ID
- 5395
- UniProt
- P54278
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