CD11b 抗体
Quick Overview for CD11b 抗体 (ABIN7468485)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Affinity purified by Protein G.
-
免疫原
- The immunogen used to generate this antibody corresponds to human CD11b.
-
亚型
- IgG2b
-
-
-
-
应用备注
- FACS: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, No Preservative
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
别名
- integrin subunit alpha M
-
背景
-
Synonyms: integrin subunit alpha M , CD11B , CR3A , MAC-1 , MAC1A , MO1A , SLEB6
Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
-
分子量
- 127 kDa
-
基因ID
- 3684
-
UniProt
- P11215
-
途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
-