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GBA3 抗体

This 兔 多克隆 anti-GBA3 antibody specifically detects GBA3 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7468369
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GBA3 抗体 (ABIN7468369)

抗原

See all GBA3 抗体
GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

适用

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宿主

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克隆类型

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多克隆

标记

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This GBA3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human GBA3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Jurkat

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.55 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

    别名

    glucosylceramidase beta 3 (gene/pseudogene)

    背景

    Synonyms: glucosylceramidase beta 3 (gene/pseudogene) , CBG , CBGL1 , GLUC , KLRP

    Background: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM]

    分子量

    54 kDa

    基因ID

    57733

    UniProt

    Q9H227
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