EGLN1 抗体 (C-Term)
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Quick Overview for EGLN1 抗体 (C-Term) (ABIN7468296)
抗原
See all EGLN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PHD2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-426) antibody
KO Validated EGLN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 42-140) antibodyEGLN1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 272-355) antibodyEGLN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (Internal Region) antibodyEGLN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) antibodyEGLN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-24) antibodyEGLN1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal 366G-76-3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (C-Term) antibodyEGLN1 适用: 人, 小鼠, 大鼠, 兔, 犬, 猴, Cow, 豚鼠, 马, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 300-400) antibodyEGLN1 适用: 小鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa(200 μM CoCl2 treatment for 24 hr) Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.99 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
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别名
- egl-9 family hypoxia inducible factor 1
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背景
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Synonyms: egl-9 family hypoxia inducible factor 1 , C1orf12 , ECYT3 , HALAH , HIF-PH2 , HIFPH2 , HPH-2 , HPH2 , PHD2 , SM20 , ZMYND6
Background: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq]
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分子量
- 46 kDa
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基因ID
- 54583
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UniProt
- Q9GZT9
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途径
- cAMP Metabolic Process, Warburg Effect
抗原
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