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DPF1 抗体

This anti-DPF1 antibody (ABIN7468200) is a Rabbit Polyclonal antibody detecting DPF1 in WB. Suitable for Human.
产品编号 ABIN7468200
发货至: 中国

Quick Overview for DPF1 抗体 (ABIN7468200)

抗原

See all DPF1 抗体
DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

适用

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宿主

  • 15
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克隆类型

  • 16
多克隆

标记

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This DPF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human DPF1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: IMR32 , U87-MG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.85 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

    别名

    double PHD fingers 1

    背景

    Synonyms: double PHD fingers 1 , BAF45b , NEUD4 , neuro-d4

    Background: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

    分子量

    43 kDa

    基因ID

    8193

    UniProt

    Q92782
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