DPF1 抗体
Quick Overview for DPF1 抗体 (ABIN7468200)
抗原
See all DPF1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            交叉反应
- 人
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Recombinant protein encompassing a sequence within the center region of human DPF1. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Positive Control: IMR32 , U87-MG 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 0.85 mg/mL
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                                            缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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                                            储存液
- Thimerosal (Merthiolate)
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                                            注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))
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                                            别名
- double PHD fingers 1
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                                            背景
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                        Synonyms: double PHD fingers 1 , BAF45b , NEUD4 , neuro-d4 Background: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. 
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                                            分子量
- 43 kDa
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                                            基因ID
- 8193
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                                            UniProt
- Q92782
 抗原
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