Exportin 2 抗体
Quick Overview for Exportin 2 抗体 (ABIN7468178)
抗原
See all Exportin 2 (CSE1L) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Affinity purified by Protein G.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.
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亚型
- IgG2b
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2 , 293T Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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别名
- chromosome segregation 1 like
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背景
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Synonyms: chromosome segregation 1 like , CAS , CSE1 , XPO2
Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]
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分子量
- 110 kDa
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基因ID
- 1434
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UniProt
- P55060
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途径
- Protein targeting to Nucleus
抗原
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