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Exportin 2 抗体

This anti-Exportin 2 antibody is a 小鼠 单克隆 antibody detecting Exportin 2 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7468178
发货至: 中国
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Quick Overview for Exportin 2 抗体 (ABIN7468178)

抗原

See all Exportin 2 (CSE1L) 抗体
Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

适用

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宿主

  • 39
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小鼠

克隆类型

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单克隆

标记

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This Exportin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

质量等级

KO Validated

克隆位点

GT5111
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.

    亚型

    IgG2b
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2 , 293T Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

    别名

    chromosome segregation 1 like

    背景

    Synonyms: chromosome segregation 1 like , CAS , CSE1 , XPO2

    Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]

    分子量

    110 kDa

    基因ID

    1434

    UniProt

    P55060

    途径

    Protein targeting to Nucleus
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