CDC6 抗体
Quick Overview for CDC6 抗体 (ABIN7468126)
抗原
See all CDC6 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CDC6. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Neuro2A , GL261 , C8D30 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2 , Jurkat , HeLa (10 mM Hydroxyurea treatment for 18 hr) Validation: Comparison, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.36 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
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别名
- cell division cycle 6
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背景
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Synonyms: cell division cycle 6 , CDC18L , HsCDC18 , HsCDC6 , MGORS5
Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq]
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分子量
- 63 kDa
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基因ID
- 990
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UniProt
- Q99741
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途径
- DNA Replication, Synthesis of DNA
抗原
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