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ARID1A 抗体 (C-Term)

ARID1A 适用: 人 WB, IF, IHC (p), ICC 宿主: 小鼠 Monoclonal GT3611 unconjugated
产品编号 ABIN7467969
发货至: 中国
  • 抗原 See all ARID1A 抗体
    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
    抗原表位
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 33
    • 19
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 31
    • 2
    小鼠
    克隆类型
    • 24
    • 9
    单克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ARID1A antibody is un-conjugated
    应用范围
    • 12
    • 7
    • 4
    • 4
    • 2
    • 2
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    纯化方法
    Affinity purified by Protein G.
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A. The exact sequence is proprietary.
    克隆位点
    GT3611
    亚型
    IgG1
    Top Product
    Discover our top product ARID1A Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.61 mg/mL
    缓冲液
    PBS, No Preservative
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
    别名
    AT-rich interaction domain 1A (ARID1A 产品)
    别名
    B120 antibody, BAF250 antibody, BAF250a antibody, BM029 antibody, C1orf4 antibody, ELD antibody, MRD14 antibody, OSA1 antibody, P270 antibody, SMARCF1 antibody, hELD antibody, hOSA1 antibody, 1110030E03Rik antibody, Osa1 antibody, Smarcf1 antibody, ARID1A antibody, wu:fb79b07 antibody, wu:fb95g08 antibody, zgc:171438 antibody, AT-rich interaction domain 1A antibody, AT rich interactive domain 1A (SWI-like) antibody, AT rich interactive domain 1Aa (SWI-like) antibody, ARID1A antibody, Arid1a antibody, arid1a antibody, arid1aa antibody
    背景

    Synonyms: AT-rich interaction domain 1A , B120 , BAF250 , BAF250a , BM029 , C1orf4 , CSS2 , ELD , MRD14 , OSA1 , P270 , SMARCF1 , hELD , hOSA1

    Background: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    分子量
    242 kDa
    基因ID
    8289
    UniProt
    O14497
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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