PABPC4 抗体
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北京 101111
Quick Overview for PABPC4 抗体 (ABIN7467853)
抗原
See all PABPC4 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 斑马鱼
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PABPC4. The exact sequence is proprietary.
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亚型
- IgG
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anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 350-450) antibody
PABPC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Internal Region) antibodyPABPC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 181-230) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 18-229) antibodyPABPC4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (N-Term) antibodyPABPC4 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 1-660) antibodyPABPC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 432-481) antibodyPABPC4 适用: 人, 大鼠, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Middle Region) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (N-Term) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
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别名
- poly(A) binding protein cytoplasmic 4
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背景
- Poly(A) binding protein cytoplasmic 4 , APP-1 , APP1 , PABP4 , iPABP,Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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分子量
- 71 kDa
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基因ID
- 8761
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UniProt
- Q13310
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途径
- SARS-CoV-2 Protein Interactome
抗原
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