PABPC4 抗体 (Middle Region)
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- 抗原 See all PABPC4 抗体
- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PABPC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RPNPRWQQGG RPQGFQGMPS AIRQSGPRPT LRHLAPTGSE CPDRLAMDFG
- 预测反应
- Cow: 93%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PABPC4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PABPC4
- Top Product
- Discover our top product PABPC4 Primary Antibody
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anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 350-450) antibody
PABPC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Internal Region) antibodyPABPC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 181-230) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 18-229) antibodyPABPC4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 432-481) antibodyPABPC4 适用: 人, 大鼠, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 1-660) antibodyPABPC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (N-Term) antibodyPABPC4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 644 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 39, Issue 8, pp. 369-74, (2012) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 39, Issue 8, pp. 369-74, (2012) (PubMed).
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- 抗原
- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
- 别名
- PABPC4 (PABPC4 产品)
- 别名
- cb12 antibody, sb:cb12 antibody, PABP antibody, ePAB antibody, ePABP antibody, APP-1 antibody, APP1 antibody, PABP4 antibody, iPABP antibody, polyadenylate-binding protein 4 antibody, poly(A) binding protein, cytoplasmic 4 antibody, poly(A) binding protein, cytoplasmic 4 (inducible form) antibody, poly(A) binding protein cytoplasmic 4 L homeolog antibody, poly(A) binding protein cytoplasmic 4 antibody, Bm1_06880 antibody, Pabpc4 antibody, pabpc4 antibody, pabpc4.L antibody, PABPC4 antibody
- 背景
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Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: APP-1, APP1, PABP4, iPABP
Protein Interaction Partner: FBXW11, UBC, IVNS1ABP, STAU1, RPA3, RPA2, RPA1, WWOX, SUZ12, RNF2, EZH2, BMI1, NCAPD2, DDX5, TARDBP, SRPK2, CLK3, YWHAQ, UBD, EIF2AK2, PAN2, UBL4A, SMAD9, ITGA4, IL7R, IFIT3, IFIT1, IFIT2, FN1, IGBP1, NUBP2, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A,
Protein Size: 644 - 分子量
- 71 kDa
- 基因ID
- 8761
- NCBI登录号
- NM_003819, NP_003810
- UniProt
- Q13310
- 途径
- SARS-CoV-2 Protein Interactome
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