PRMT5 抗体
Quick Overview for PRMT5 抗体 (ABIN7467758)
抗原
See all PRMT5 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PRMT5. The exact sequence is proprietary.
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亚型
- IgG
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anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 40-140) antibody
PRMT5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (Internal Region) antibodyPRMT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 21-70) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 猴, 豚鼠, Pig, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 297-534) antibodyPRMT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人, 小鼠 WB, IHC, IF, IP, ChIP, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 591-621) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 76-104) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.31 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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别名
- protein arginine methyltransferase 5
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背景
- Protein arginine methyltransferase 5 , HRMT1L5 , HSL7 , IBP72 , JBP1 , SKB1 , SKB1Hs,Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
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分子量
- 73 kDa
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基因ID
- 10419
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UniProt
- O14744
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
抗原
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