DCLK1 抗体
Quick Overview for DCLK1 抗体 (ABIN7467612)
抗原
See all DCLK1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human DCLK1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibody
DCLK1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6H4 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 690-720) antibodyDCLK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB3161 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 143-381) antibodyDCLK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibodyDCLK1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 1-30), (N-Term) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3059 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1751CT665-1-72 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F9 unconjugated
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应用备注
- WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , mouse hippocampus , mouse brain , rat brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.77 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
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别名
- doublecortin like kinase 1
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背景
- Doublecortin like kinase 1 , CL1 , CLICK1 , DCAMKL1 , DCDC3A , DCLK,This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010]
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分子量
- 82 kDa
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基因ID
- 9201
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UniProt
- O15075
抗原
-
