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LIG4 抗体 (C-Term)

Name: LIG4 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN7467576
Availability: OutOfStock

This anti-LIG4 antibody is a 兔多克隆 antibody detecting LIG4 in WB, IF, ICC 和 IHC (p). Suitable for 人.

产品编号 ABIN7467576

发货至: 中国

Quick Overview for LIG4 抗体 (C-Term) (ABIN7467576)

抗原

See all LIG4 抗体

LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

适用

人

宿主

兔

克隆类型

多克隆

标记

This LIG4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product LIG4 Primary Antibody

抗原表位
15

3

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2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human DNA ligase IV. The exact sequence is proprietary.

亚型

IgG
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (C-Term) antibody
LIG4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 612-911) antibody
LIG4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibody
LIG4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 275-324) antibody
LIG4 适用: 人, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibody
KO Validated LIG4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 802-911) antibody
LIG4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D2 unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibody
LIG4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (Center) antibody
LIG4 适用: 人, Cow, 犬 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibody
LIG4 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 1-911) antibody
LIG4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: U87-MG , mouse brain , rat brain

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

别名

DNA ligase 4

背景

DNA ligase 4 , LIG4S,The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

分子量

104 kDa

基因ID

3981

UniProt

P49917

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response