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PPL 抗体 (N-Term)

This anti-PPL antibody is a 兔 多克隆 antibody detecting PPL in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7467493
发货至: 中国
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Quick Overview for PPL 抗体 (N-Term) (ABIN7467493)

抗原

See all PPL 抗体
PPL (Periplakin (PPL))

适用

  • 31
  • 9
  • 7
  • 1

宿主

  • 31
  • 2

克隆类型

  • 33
多克隆

标记

  • 24
  • 3
  • 2
  • 2
  • 1
  • 1
This PPL antibody is un-conjugated

应用范围

  • 30
  • 20
  • 10
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human Periplakin. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PPL (Periplakin (PPL))

    别名

    periplakin

    背景

    Periplakin,The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq]

    分子量

    205 kDa

    基因ID

    5493

    UniProt

    O60437
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