PPL 抗体 (C-Term)
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- 抗原 See all PPL 抗体
- PPL (Periplakin (PPL))
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抗原表位
- AA 1664-1701, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Periplakin(PPL) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- DTGRELSPEE AHRAGLIDWN MFVKLRSQEC DWEEISVK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Periplakin(PPL) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: periplakin
Protein Name: Periplakin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Periplakin (1664-1701aa DTGRELSPEEAHRAGLIDWNMFVKLRSQECDWEEISVK), different from the related mouse sequence by one amino acid.
- 亚型
- IgG
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anti-Periplakin (PPL) (AA 1664-1701) antibody
PPL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1301-1330) antibodyPPL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1-130) antibodyPPL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1501-1754) antibodyPPL 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) antibodyPPL 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) antibodyPPL 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1044-1093) antibodyPPL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1-130) antibodyPPL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1439-1716) antibodyPPL 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1301-1330), (C-Term) antibodyPPL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- PPL (Periplakin (PPL))
- 别名
- PPL (PPL 产品)
- 别名
- cb180 antibody, sb:cb180 antibody, im:7140067 antibody, im:7149519 antibody, AW553870 antibody, periplakin antibody, periplakin L homeolog antibody, PPL antibody, ppl antibody, ppl.L antibody, Ppl antibody
- 背景
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Periplakin is a protein that in humans is encoded by the PPL gene. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
Synonyms: Periplakin | ppl | O60437 - 基因ID
- 5493
- UniProt
- O60437
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