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X-Ray Repair Cross Complementing 5 (N-Term) 抗体

适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal 9403 unconjugated
产品编号 ABIN7467423
发货至: 中国
  • 抗原
    X-Ray Repair Cross Complementing 5
    抗原表位
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 7
    • 2
    宿主
    • 4
    • 4
    小鼠
    克隆类型
    • 4
    • 4
    单克隆
    标记
    • 8
    非结合性
    应用范围
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Protein G purified
    免疫原
    Recombinant antigen containing the amino terminal portion of human Ku80 protein
    克隆位点
    9403
    亚型
    IgG1
  • 应用备注
    WB: 1:1000-1:5000. ICC/IF: 1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: T24 , Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, No Preservative
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    X-Ray Repair Cross Complementing 5
    别名
    KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, Ku86 antibody, NFIV antibody, AI314015 antibody, Ku80 antibody, X-ray repair cross complementing 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 antibody, XRCC5 antibody, Xrcc5 antibody
    背景
    X-ray repair cross complementing 5 , KARP-1 , KARP1 , KU80 , KUB2 , Ku86 , NFIV,The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
    分子量
    83 kDa
    基因ID
    7520
    UniProt
    P13010
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