X-Ray Repair Cross Complementing 5 (C-Term) 抗体
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北京 101111
Quick Overview for X-Ray Repair Cross Complementing 5 (C-Term) 抗体 (ABIN7464656)
抗原
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- C-Term
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交叉反应
- 人, 猴
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纯化方法
- Protein G purified
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免疫原
- Recombinant antigen containing the carboxy terminal portion of human Ku80 protein
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亚型
- IgG1
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anti-X-Ray Repair Cross Complementing 5 antibody
适用: 人 WB, IP, ICC, IF, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Cross Complementing 5 antibody适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2045 unconjugated Recombinant Antibody
anti-X-Ray Repair Cross Complementing 5 (AA 441-490) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- X-Ray Repair Cross Complementing 5
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背景
- X-ray repair cross complementing 5 , KARP-1 , KARP1 , KU80 , KUB2 , Ku86 , NFIV,The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
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分子量
- 83 kDa
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基因ID
- 7520
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UniProt
- P13010
抗原
-
