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Cyclin D2 抗体 (N-Term)

This anti-Cyclin D2 antibody is a 兔 多克隆 antibody detecting Cyclin D2 in WB, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN7467394
发货至: 中国

Quick Overview for Cyclin D2 抗体 (N-Term) (ABIN7467394)

抗原

See all Cyclin D2 (CCND2) 抗体
Cyclin D2 (CCND2)

适用

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宿主

  • 68
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克隆类型

  • 71
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多克隆

标记

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This Cyclin D2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Cyclin D2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: RD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.97 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Cyclin D2 (CCND2)

    别名

    cyclin D2

    背景

    Cyclin D2 , KIAK0002 , MPPH3,The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq]

    分子量

    33 kDa

    基因ID

    894

    UniProt

    P30279

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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