MADD 抗体
Quick Overview for MADD 抗体 (ABIN7466967)
抗原
See all MADD 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse MADD. The exact sequence is proprietary.
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亚型
- IgG
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anti-MAP-Kinase Activating Death Domain (MADD) (Internal Region) antibody
MADD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (Internal Region) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (AA 751-800) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (C-Term) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Neuro2A , Raw264.7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.39 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MADD (MAP-Kinase Activating Death Domain (MADD))
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别名
- MAP-kinase activating death domain
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背景
- MAP-kinase activating death domain , 9630059K23Rik , IG20,Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis).
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分子量
- 175 kDa
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基因ID
- 228355
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UniProt
- Q80U28
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途径
- Caspase Cascade in Apoptosis
抗原
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