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MADD 抗体

This anti-MADD antibody is a 兔 多克隆 antibody detecting MADD in WB. Suitable for 小鼠.
产品编号 ABIN7466967
发货至: 中国

Quick Overview for MADD 抗体 (ABIN7466967)

抗原

See all MADD 抗体
MADD (MAP-Kinase Activating Death Domain (MADD))

适用

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小鼠

宿主

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克隆类型

  • 39
  • 12
多克隆

标记

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This MADD antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse MADD. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Neuro2A , Raw264.7

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.39 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    MADD (MAP-Kinase Activating Death Domain (MADD))

    别名

    MAP-kinase activating death domain

    背景

    MAP-kinase activating death domain , 9630059K23Rik , IG20,Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis).

    分子量

    175 kDa

    基因ID

    228355

    UniProt

    Q80U28

    途径

    Caspase Cascade in Apoptosis
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