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MADD 抗体

MADD 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7466967
发货至: 中国
  • 抗原 See all MADD 抗体
    MADD (MAP-Kinase Activating Death Domain (MADD))
    适用
    • 21
    • 14
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 21
    克隆类型
    • 20
    • 1
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MADD antibody is un-conjugated
    应用范围
    • 12
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse MADD. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MADD Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Neuro2A , Raw264.7

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.39 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MADD (MAP-Kinase Activating Death Domain (MADD))
    别名
    MAP-kinase activating death domain (MADD 产品)
    背景
    MAP-kinase activating death domain , 9630059K23Rik , IG20,Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis).
    分子量
    175 kDa
    基因ID
    228355
    UniProt
    Q80U28
    途径
    Caspase Cascade in Apoptosis
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